2'-(4-METHYLUMBELLIFERYL)-ALPHA-D-N-ACETYLNEURAMINIC ACID SODIUM SALT CAS:76204-02-9

2'-(4-Methylumbelliferyl)-alpha-D-N-acetylneuraminic acid sodium salt is a chemical compound commonly used in diagnostic and research assays. It is a fluorescently labeled derivative of sialic acid, a type of carbohydrate molecule found on the surface of cells. This compound is used as a substrate for enzymes called neuraminidases, which act to remove sialic acid residues from glycoproteins and glycolipids. When these enzymes act on the 2'-(4-Methylumbelliferyl)-alpha-D-N-acetylneuraminic acid sodium salt, it releases a fluorescent product known as 4-methylumbelliferone. The fluorescence generated by the compound can be measured and quantified, providing information on the activity of neuraminidase enzymes. This is particularly useful in the study of various diseases and conditions associated with aberrant sialic acid metabolism. The compound is also utilized for diagnostic purposes, such as in the detection of viral infections that involve neuraminidase activity. In these assays, the compound is used to identify the presence of specific viral strains or assess the effectiveness of neuraminidase inhibitors in antiviral treatments.

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Application and Effect

Neuraminidase Activity Assay: This compound is commonly used to measure the activity of neuraminidase enzymes in biological samples. By monitoring the fluorescence generated, researchers can determine the level of neuraminidase activity, which can help in the study of various diseases and conditions. Viral Infection Detection: Many viral infections, including influenza, involve neuraminidase activity. This compound can be used to detect and quantify the presence of specific viral strains by measuring fluorescent activity. It is particularly useful in assessing the effectiveness of neuraminidase inhibitors in antiviral treatments. Glycosylation Analysis: Sialic acid is an important component of glycoproteins and glycolipids. By incorporating 2'-(4-Methylumbelliferyl)-alpha-D-N-acetylneuraminic acid sodium salt into experiments, researchers can gain insights into sialic acid metabolism, glycosylation patterns, and related physiological processes. Drug Discovery: Neuraminidase inhibitors are a class of drugs used in the treatment of viral infections. This compound can be used in drug discovery studies, helping researchers identify and evaluate potential inhibitors of neuraminidase activity.  

Product Packing:

Additional Information:

Composition C21H26NNaO11
Assay 99%
Appearance White powder
CAS No. 76204-02-9
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.
 

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